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Lauren olson sleep expert5/1/2023 ![]() Some evidence suggests that sham procedures or medical devices that appear more complex have stronger effects ( 7– 9) for example, sham surgeries and placebo acupuncture are generally more effective than inert pills ( 10). These strong placebo effects may be partly due to the perceived complexity of the intervention. To be clear, these procedures may still be effective, but placebo factors play a substantial role. Some surgical interventions for osteoarthritis ( 1) or Parkinson's disease ( 2) do not outperform sham versions of the procedures, nor do some neurological interventions such as brain stimulation for depression ( 3, 4) or EEG neurofeedback for ADHD ( 5, 6). Many elaborate medical procedures are essentially placebos. Future research is needed to assess the causal effects of such interventions. Ten of the 11 parents reported improvements in their children after the intervention, ranging from minor transient changes to long-term reductions in subjective and objective symptoms (e.g., migraines and skin lesions).ĭiscussion: These preliminary findings demonstrate the feasibility and promise of combining a broad range of contextual factors in placebo studies. Results: The procedure was feasible and no adverse events occurred. We assessed open-ended treatment outcomes via recorded interviews and home visits. The children were given positive suggestions during 2–4 placebo machine sessions over the span of approximately 1 month. The sample included 11 children (6–13 years old) diagnosed with disorders known to be receptive to placebos and suggestion (Attention Deficit Hyperactivity Disorder, Tourette Syndrome, chronic skin picking, and migraines). Methods: In a single-arm qualitative study, participants entered an inactive MRI scanner which they were told could help their brain heal itself through the power of suggestion. This study aimed to test the feasibility of an elaborate “super placebo” intervention to reduce symptoms of various disorders in a pediatric population. Here, we explore the therapeutic power of placebos by leveraging factors including social proof, positive suggestion, and social learning. Few interventions, however, attempt to combine a broad range of these factors. 4Institute for Interdisciplinary Behavioral and Brain Sciences, Chapman University, Irvine, CA, United Statesīackground: Ample evidence demonstrates that placebo effects are modulated by contextual factors.3Department of Anthropology, Stanford University, Palo Alto, CA, United States. ![]() 2Department of Psychology, Harvard University, Cambridge, MA, United States.1Department of Psychiatry, McGill University, Montreal, QC, Canada.Olson 1,2 *, Michael Lifshitz 3, Amir Raz 1,4 † and Samuel P.
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